Electrostatic Modeling Predicts the Activities of Orthopoxvirus Complement Control Proteins
نویسندگان
چکیده
منابع مشابه
Electrostatic modeling predicts the activities of orthopoxvirus complement control proteins.
Regulation of complement activation by pathogens and the host are critical for survival. Using two highly related orthopoxvirus proteins, the vaccinia and variola (smallpox) virus complement control proteins, which differ by only 11 aa, but differ 1000-fold in their ability to regulate complement activation, we investigated the role of electrostatic potential in predicting functional activity. ...
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ژورنال
عنوان ژورنال: The Journal of Immunology
سال: 2005
ISSN: 0022-1767,1550-6606
DOI: 10.4049/jimmunol.174.4.2143